Chemistry
Antibody-Drug Conjugates
What are Antibody-Drug Conjugates?
Antibody-Drug Conjugates (ADC) are an important new class of biopharmaceutical drugs. ADCs deliver potent anti-cancer agents directly to the target tumor. ADCs combine the targeting capabilities of monoclonal antibodies with the cancer-killing ability of cytotoxic drugs.
ADCs comprise a tumor-specific antibody connected via a chemical linker to a biologically active drug or cytotoxic compound. Combining an antibody's exquisite targeting capabilities with potent drug molecules makes these innovative therapeutics highly efficacious without the side effects of traditional chemotherapeutic agents.
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