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Genesis Drug Discovery & Development is a proud member of Genesis Drug Discovery & Development (GD3), a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-III clinical trials.
Learn more about GD3Chemistry
- Asymmetric Synthesis
- High-Speed Synthesis and purification
- Metabolite Synthesis (Phase I and II)
- Molecular Probes (Fluorophores and Biotinylated Targets)
- Structure Identification and Characterization
- Stable Isotopically Labeled Compounds (2H, 13C, 15N, 34S)
- Specific Chemistry Expertise
- Natural Product Synthesis
- Instrumentation and Computing
Instrumentation and Computing
We are fully equipped for optimal productivity
We continuously invest in capital equipment, software tools and databases to ensure we deliver the highest quality of services to our partners. Our organization provides fully equipped laboratories that offer state-of-the-art technologies, as well as highly trained and experienced chemists. Our research facility includes synthetic and medicinal chemistry laboratory space, equipped 55 chemistry fume hoods, and late-model instrumentation suitable for performing various types of chemistry to synthesize, purify and characterize the chemical compounds. In addition to the laboratory space, GD3 utilizes modern reaction databases, electronic laboratory notebooks and sub-structure searchable systems for managing chemical inventory, compound registration and biological data.
A partial equipment list includes:
- Nitrogen generator
- Hydrogenators
- Rotary evaporators with KNF pumps and digital regulators
- Freeze Dryer (lyophilizer); Hi-vacuum pumps
- HPLC/MS
- UPLC
- Preparative and analytical HPLCs equipped with UV and ELSD
- Medium-pressure liquid chromatography systems
- Large-research scale chromatography
- Chiral Technologies analytical HPLC columns
- Access to a well-equipped suite of NMR spectrophotometers (400, 500, 600, 800 MHz), UV-visible spectrometers
- ISCO
- Kessil lamp
- Photoredox Flow Reactor
- Melting-point apparatus
- Abbe refractometer
- Glass reactors for high-pressure reactions (4 mL – 1 L), 2.5 L steel-autoclave
- Scale-up glass reactors 2-25 L
- Low-temperature thermostats
- Refrigerated circulator (from -35°C up to +150°C)
- Flow chemistry reactors
- Microwave reactors
- Teflon reactor
- Flash chromatography
- LC
- Gas chromatography
- GCMS-QP
A partial equipment list includes:
- SciFinder Chemical Database (structure-searchable reaction and supplier database)
- Reaxys Reaction Database
- Accelrys Discovery Studio Visualizer
- eNovalys Electronic Laboratory Notebook (ELN)
- Biovia CisPro Chemical inventory management system (sub-structure searchable)
- Collaborative Drug Discovery (cloud-based bioinformatics software package that includes compound registration)
- Biological assay data with mining tools
- Structure-activity tables and project management applications
- Microsoft Office Suite (Outlook, Word, Excel, PowerPoint)
- ChemDraw
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