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Genesis Drug Discovery & Development is a proud member of Genesis Drug Discovery & Development (GD3), a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-III clinical trials.
Learn more about GD3Disease Modeling
In Vivo Assays
In vivo assays provide crucial data about potential biological effects, activity, and potency. They can help assess signal transduction and receptor binding ability for a drug or biologic. We design, optimize, validate and execute bioassays to generate meaningful translational data that researchers can use to make informed decisions about which drug candidates to advance into clinical trials and ultimately bring to market for the treatment of various diseases. Our in vivo assays include
- In vivo T-cell proliferation
- In vivo antibody response characterization
- Keyhole limpet hemocyanin (KLH)-stimulated
- Ovalbumin (OVA)-stimulated
- Non-lethal endotoxemia
- LPS injection-induced for serum cytokines
- Cytokine storm
- Delayed type hypersensitivity
- Monocyte or neutrophil infiltration
- Thioglycollate-induced
- Zymosan-induced
- Curdlan-induced
- Trypsin-induced
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