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Genesis Drug Discovery & Development is a proud member of Genesis Drug Discovery & Development (GD3), a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-III clinical trials.
Learn more about GD3Disease Modeling
Behavioral Models
GD3 has deep expertise in behavioral and pain models to understand the efficacy and safety of your treatments in these areas. Our team of experts can guide you in the development of your study design, the selection of appropriate readout and the interpretation of your data.
- Behavioral-Anxiety Assessment Models
- Open field for locomotor activity (LMA) and anxiety
- Elevated plus maze for anxiety
- Precipitated opiate withdrawal
- Readouts and assessments:
- SHIRPA behavioral battery or Irwin test
- Rotarod
- Serum corticosterone
- Grip strength
- Pain Assessment Models
- Carrageenan-induced mechanical hyperalgesia
- CFA-induced challenge with thermal hyperalgesia
- Hot-plate test for thermal pain
- Mechanical allodynia by manual von Frey
- Thermal hyperalgesia by Hargreaves
- Tail flick
- Acetic acid writhing test
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