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Genesis Drug Discovery & Development is a proud member of Genesis Drug Discovery & Development (GD3), a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-III clinical trials.
Learn more about GD3Disease Modeling
Inflammation and Autoimmune Models
Our multidisciplinary scientific team offers a broad spectrum of immunology disease models, and bioassays focused on inflammation and autoimmunity through tailored individual studies designed to meet your drug discovery research needs. Our models are well-established and thoroughly validated, and we can adapt them or develop new ones to meet your needs. A clear and comprehensive final report, including statistical data analysis and complete raw data sets, is provided to accelerate your development process. These models provide valuable insights into disease pathogenesis and help accelerate the development of novel therapies for inflammatory and autoimmune diseases.
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GD3 offers the following Inflammation & Autoimmune Disease Models:
- LUNG Disease Models:
- Allergen-induced Pulmonary Inflammation for Asthma
- Lung Fibrosis
- Airway Inflammation Induced by Lipopolysaccharide
- Lethal Endotoxemia (Septic Shock)
- IBD Models:
- Dextran sulfate sodium (DSS)-induced
- Trinitrobenzene sulfonic acid (TNBS)-induced
- Skin Disease Models:
- Atopic Dermatitis
- Dermatitis
- Psoriasis
- Wound Healing
- Kidney Disease:
- Systemic Lupus Erythematosus (SLE)
- Unilateral Ureter Obstruction (UUO)
- CNS Models:
- Experimental Autoimmune Encephalitis (EAE) for Multiple Sclerosis (MS)
- Myasthenia Gravis (MG)
- Rheumatoid Arthritis:
- mBSA-induced Arthritis
- Collagen-induced Arthritis
- Monoclonal Antibody-induced Arthritis
- Primary Biliary Cholangitis (PBC)
- Graft-versus-Host Disease (GvHD)