Publications

Somasundaram P, Farley MM, Rudy MA, Stefanoff DG, Shah M, Goli P, Heo J, Wang S, Tran NM, Watkins TA. 2023. Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by Atf4 following optic nerve injury. eLife [Preprint].:2023.03.29.534798. doi: 10.1101/2023.03.29.534798 PMID: 37034690

Donthireddy L, Vonteddu P, Murthy T, Kwak T, Eraslan R, Podojil JR, Elhofy A, Boyne MT, Puisis JJ, Veglia F, Singh SS, Dotiwala F, Montaner LJ, Gabrilovich DI. 2022. ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts. J Cancer 28;13(6):1933-1944 (2022) PMID: 35399717

Zaworski PG, Schwartz R, Burr J, Skutnik D, Mollin A, Kumar B, Ngumah Q, Welch E, Johnson B, Narasimhan J, Weetall M. 2022. Quantitation of Pax-6 protein in ocular impression cytology samples using an electrochemiluminescence immunoassay. Anal Biochem 1;656:114876. Epub 2022 Sep 2. PMID: 36058293

Karla K. Frietze, Alyssa M. Brown, Dividutta Das, Raymond G. Franks, Jessie Lee Cunningham, Michael Hayward, Joseph T. Nickels. 2022. Lipotoxicity reduces Rig-1 expression and activity leading to impaired autophagy and cell death. Autophagy, 2022, VOL. 18, NO. 1, 142–160 https://doi.org/10.1080/15548627.2021.1920818

Maillet E, Skutnik D, Jamison JA, Bailey D, Bacellar-Galdino M, & Garlick D. 2021. 2021. Anti-Inflammatory and Protective Effects of Topical Opthlamic (R)-DOI 0.01% in Allergic Conjunctivitis and Recurrent Intermediate Uveitis Disease Models in Rabbits. IOVS June 2021. 62, 232.

Gupta, A., Gullapalli, S., Pan, H. Ramos-Ortolaza, D. L., Hayward, M.D., Low, M.J. Pintar, J.E. Devi, L.A. I. 2021. Gomes Regulation of Opioid Receptors by Their Endogenous Opioid Peptides. Cell Mol Neurobiol 2021 July ; 41(5): 1103–1118. https://doi.org/10.1007%2Fs10571-020-01015-w

Christiano R. R. Alves PhD1, Ren Zhang MPH1, Alec J. Johnstone BS1, Reid Garner BS1, Eric J. Eichelberger BS1, Salomé Da Silva Duarte Lepez BA1, Vivian Yi BS1, Victoria Stevens B.S.1, Rebekah Poxson BA2, Rachel Schwartz BA2, Phillip Zaworski MS2, Kathryn J. Swoboda. 2020. MD1 Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy Muscle and Nerve DOI: 10.1002/mus.26995 2020 In Press

Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I. 2020. Cholesterol Pathway Inhibition Induces TGF-? Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell 38(4):567-583. e11. doi: 10.1016/j.ccell.2020.08.015. Epub 2020 Sep 24 PMID: 32976774

Makhov P, Sohn JA, Serebriiskii IG, Fazliyeva R, Khazak V, Boumber Y, Uzzo RG, Kolenko VM. 2020. CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma. Br J Cancer Sep 24. doi: 10.1038/s41416-020-01087-x. Online ahead of print.

Tarpinian S, Rowe J, Husanov R, Saha U, Banerjee P, Eraslan R, Jones B, Festin S, Khazak V. 2020. Invivotek, Hamilton, NJ. NexusPharma, Philadelphia, PA. Charles River Laboratories Research Models and Services (RMS), Wilmington, MA. Assessment of sensitivity to a PD-1 check point inhibitor and cisplatin in bladder cancer patient-derived xenografts with various levels of PD-L1 expression in HuCD34NCG mice. Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs (SITC 2020); November 9-14, 2020; Virtual.

Muhua Yang, Christina Gallo-Ebert, Michael Hayward, Weidong Liu, Virginia McDonough and Joseph T. Nickels, Jr. 2020. Human insulin growth factor 2 mRNA binding protein 2 increases miR-33a/b inhibition of liver ABCA1 expression and alters low-density apolipoprotein levels in mice Mol and Cell Biol. 2020 Aug; 40(16): e00058-20. DIO: https://doi.org/10.1128%2FMCB.00058-20

Ramos DM, d'Ydewalle C, Gabbeta V, Dakka A, Klein SK, Norris DA, Matson J, Taylor SJ, Zaworski PG, Prior TW, Snyder PJ, Valdivia D, Hatem CL, Waters I, Gupte N, Swoboda KJ, Rigo F, Bennett CF, Naryshkin N, Paushkin S, Crawford TO, Sumner CJ. 2019. Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. Clin Invest https://doi.org/10.1172/JCI124120. [Epub ahead of print] PMID: 31589162

Krais J, Clausen E, Khazak V, Astsaturov I, Scott CL, Johnson N. 2019. Assessment of PARPi and cisplatin resistance in BRCA1 exon 11 mutant patient-derived xenografts. American Association for Cancer Research (AACR) Special Conference on Advances in Ovarian Cancer Research; September 13-16, 2019; Atlanta, GA.

Michael C. Van Zandt, G. Erik Jagdmann, Darren L. Whitehouse, Minkoo Ji, Jennifer Savoy, Olga Potapova, Alexandra Cousido-Siah, Andre Mitschler, Eduardo I. Howard, Anna Marie Pyle, and Alberto D. Podjarny. 2019. Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II

Gallo-Ebert C, Francisco J, Liu HY, Draper R, Modi K, Hayward MD, Jones BK, Buiakova O, McDonough V, Nickels, JT Jr. 2018. Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. J Biol Chem 296(16): 5956-5974 2018

Stroke, IL, Letourneau, JJ, Miller, TE, Xu, Y, Pechik, I, Savoly, DR, Ma, L, Sturzenbecker, LJ, Sabalski, J, Stein, PD, Webb, ML, Hilbert, DW. 2018. Treatment of Clostridium difficile infection with a small molecule inhibitor of toxin UDP-glucose hydrolysis activity. Antimicrob. Agents Chemother. (2018), 62, e00107-18

Letourneau, JJ, Stroke, IL, Hilbert, DW, Sturzenbecker, LJ, Marinelli, BA, Quintero, JG, Sabalski, J, Ma, L, Diller, DJ, Stein, PD, Webb, ML. 2018. Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB). Bioorganic & Medicinal Chemistry Letters (2018), 28(4), 756-7

Strathmann EA, Peters M, Hosseinibarkooie S, Rigo FW, Bennett CF, Zaworski PG, Chen KS, Nothnagel M. 2018. Wirth B. Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice. PLoS One. 2018 Sep 6;13(9):e0203398. doi: 10.1371/journal.pone.0203398. eCollection

Iyer CC, Corlett KM, Massoni-Laporte A, Duque SI, Madabusi N, Tisdale S, McGovern VL, Le TT, Zaworski PG, Arnold WD, Pellizzoni L, Burghes. 2018. Mild SMN missense alleles are only functional in the presence of SMN2 in mammals. AHM.Hum Mol Genet. 2018 Oct 1;27(19):3404-3416. doi: 10.1093/hmg/ddy251 PMID: 29982416

Decker DE, Skutnik D, Burr J, Pattison C, Cooley-Themm C, Linn DM, & Linn CL. 2018. 2018. GDF-15 Levels increase in Aqueous Humor Following Hypertonic Saline Injection into the Episcleral Vein in a Rat Claucoma Model. IOVS July 2018. 59, 3504.

Lisa D Berman-Booty , Rukiye Eraslan, Umesh Hanumegowda, Glenn H Cantor , Denise I Bounous , Evan B Janovitz, Beverly K Jones , Olesia Buiakova, Michael Hayward, Susan Wee. 2018. Systemic Loss of C-terminal Src Kinase (CSK) Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice. Vet Pathol 2018 Mar;55(2):331-340

Fedorova, Olga; Jagdmann, G. Erik; Adams, Rebecca L.; Yuan, Lin; Van Zandt, Michael; Pyle, Anna Marie . 2018. Small molecules that target group II introns are potent antifungal agents, Nature Chemical Biology (2018), 14 (12), 1073-1078 PMID: 30323219

Van Zandt, Michael C.; Savoy, Jennifer L.. 2018. Method of preparing (3r,4s)-3-acetamido-4-allyl-n-(tert-butyl) pyrrolidine-3-carboxamide, WO 2018209290 A1, 60 pp (2018)

Dworak, Jessica; Jagdmann, G. Erik; Van Zandt, Michael. 2018. Total synthesis of protectin DX, a potent proresolving lipid mediator, Abstracts of Papers, 256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018 (2018), ORGN-648

Rinis, Natalia; Golden, Jennifer E.; Marceau, Caleb D.; Carette, Jan E.; Van Zandt, Michael C.; Gilmore, Reid; Contessa, Joseph N. 2018. Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors, Cell Chemical Biology (2018), 25(10), 1231-1241.e4 PMID: 30078634

Sjogren, Eric B.; Li, Jim; Chen, Lijing; Billedeau, Roland J.; Stanton, Timothy F.; Van Zandt, Michael; Whitehouse, Darren; Jagdmann, Gunnar E., Jr.; Petersen, Lene Raunkjaer; Parlati, Francesco; et al. 2018. Preparation of boron compounds and using compositions and methods for inhibiting arginase activity, WO 2018119440 A1, 220 pp (2018)

Sciavolino, Frank C.; Mathias, Gary; Van Zandt, Michael; Jagdmann, G. Erik; Dworak, Jessica. 2018. Compositions and methods relating to salts of specialized pro-resolving mediators of inflammation, WO 2017210604 A1, 109 pp (2018)

Gopinath, Smita; Kim, Myoungjoo V.; Rakib, Tasfia; Wong, Patrick W.; van Zandt, Michael; Barry, Natasha A.; Kaisho, Tsuneyasu; Goodman, Andrew L.; Iwasaki, Akiko. 2018. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner, Nature Microbiology (2018), 3(5), 611-621 PMID: 29632368

He S, Gleason J, Fik-Rymarkiewicz E, DiFiglia A, Bharathan M, Morschauser A, Djuretic I, Xu Y, Krakovsky M, Jankovic V, Buensuceso C, Edinger J, Herzberg U, Hofgartner W, Hariri R. 2017. Human Placenta-Derived Mesenchymal Stromal-Like Cells Enhance Angiogenesis via T Cell-Dependent Reprogramming of Macrophage Differentiation. Stem Cells 35(6): 1603-1613 PMID: 28233380

Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Iannaccone ST, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT. 2017. NeuroNEXT Clinical Trial Network on behalf of the NN101 SMA Biomarker Investigators. Natural history of infantile-onset spinal muscular atrophy. Ann Neurol. 2017 Dec;82(6):883-891. doi: 10.1002/ana.25101. Epub 2017 Dec 8. Free PMC article. Clinical Trial.

Sjogren, Eric B.; Li, Jim; Van Zandt, Michael; Whitehouse, Darren. . 2017. Compositions and methods for inhibiting arginase activity, WO 2017075363 A1, 54 pp (2017)

Zaworski P, von Herrmann KM, Taylor S, Sunshine SS, McCarthy K, Risher N, Newcomb T, Weetall M, Prior TW, Swoboda KJ, Chen KS, Paushkin S. 2016. SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials PLoS ONE 11(3): e0150640. PMID: 26953792

Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT, and the NeuroNEXT Clinical Trial Network and on behalf of the NN101 SMA Biomarker Investigators. 2016. Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study. Ann Clin Transl Neurol 3(2): 132-145. PMID: 26900585

Gaponova AV, Nikonova AS, Deneka A, Kopp MC, Kudinov AE, Skobeleva N, Khazak V, Ogawa LS, Cai KQ, Duncan KE, Duncan JS, Egleston BL, Proia DA, Boumber Y, Golemis EA. 2016. A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer. Clin Cancer Res. 2016 Oct 15;22(20):5120-5129. doi: 10.1158/1078-0432.CCR-15-3068.

Kolb, SJ, Coffey, CS, Yankey, JW et al. 2016. Baseline results of the NeuroNext spinal muscular atrophy infant biomarker study. Annals of Clinical and Translational Neurology, 21 January 2016;1-14

Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH. 2016. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration. PLoS One. 2016 Dec 1;11(12):e0167077. doi: 10.1371/journal.pone.0167077. eCollection 2016. PMID: 27907033

Czech C, Tang W, Bugawan T, Mano C, Horn C, Iglesias VA, Fröhner S, Zaworski PG, Paushkin S, Chen K, Kremer T. 2015. Biomarker for Spinal Muscular Atrophy: Expression of SMN in Peripheral Blood of SMA Patients and Healthy Controls. PLoS One 10(10): e0139950. PMID: 26468953

Stroke, IL, Ma, L, Letourneau, JJ, Cole, AG, Li, Y, Marinelli, BA, Malone, J, Paulish-Miller, T, Pechik, I, Quintero, JG, Sabalski, JE, Savoly, DR, Wang, A, Hilbert, DW, Gygax, S, Miller, DK, Stein, P, Webb, M. 2015. Miniaturized assays for RhoA inactivation through glucosylation by Clostridium difficile toxin. Society for Laboratory Automation and Screening 4th Annual Conference and Exhibition (Washington, D.C.) 7-11 February, 2015

Iyer, CC, McGovern, VL, Murray, JD, Gombash, SE, Zaworski, PG, Foust, KD, Janssen, PM and Burghes, AH. 2015. Low levels of survival motor neuron protein are sufficient for normal muscle function in the SMNdelta7 mouse model of SMA. Hum Mol Genet 2015;24(21):6160-73 PMID: 26276812

McGovern, VL, Iyer, CC, Arnold, WD, Gombash, SE, Zaworski, PG, Blatnik, AJ, Foust, KD and Burghes, AH. 2015. SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNdelta7 mouse model of SMA. Hum Mol Genet 2015; 24(19):5524-41 PMID: 26206889

Li J, Geisbush TR, Arnold WD, Rosen GD, Zaworski PG, Rutkove SB. 2014. A Comparison of Three Electrophysiological Methods for the Assessment of Disease Status in a Mild Spinal Muscular Atrophy Mouse Model. PLoS One 9(10): e111428.

Cherry JJ, Kobayashi DT, Lynes MM, Naryshkin NN, Tiziano FD, Zaworski PG, Rubin LL, Jarecki J. 2014. Assays for the Identification and Prioritization of Drug Candidates for Spinal Muscular Atrophy. Assay Drug Dev Technol 12(6): 315-341. PMID: 25147906

Gallo-Ebert C, Donigan M, Stroke IL, Swanson RN, Manners MT, Francisco J, Toner G, Gallagher D, Huang C-Y, Gygax SE, Webb M, Nickels JT Jr. 2014. Novel Antifungal Drug Discovery Based On Targeting Pathways Regulating The Fungal-Conserved Upc2 Transcription Factor. Antimicrob. Agents Chemother. (2014), 58(1), 258-266

Beeharry N, Banina E, Hittle J, Skobeleva N, Khazak V, Deacon S, Andrake M, Egleston BL, Peterson JR, Astsaturov I, Yen TJ. 2014. Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints. Cell Cycle;13(14):2172-91. doi: 10.4161/cc.29214

Hai, Yang; Edwards, Jennifer E.; Van Zandt, Michael C.; Hoffmann, Karl F.; Christianson, David W. 2014. Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis, Biochemistry (2014), 53(28), 4671-4684 PMID: 25007099

Beasley, JR, Huang, C-Y, Gallo-Ebert, C, Bata, A, Donigan, M, Giordano, C, Kanneganti, N, Malone, J, Sieber-McMaster, E, Nawoschik, S, O'Brien, L, Pham, Q, Severinova, E, Shi, D, Swanson, R, Tovar, K, Xu, X, Zalamea, P, Nickels, J, Stein, P., Webb, MW. 2013. Discovery and Optimization of GPBAR1 (TGR5) Agonists. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January 2013

Uveges, A, Severinova, E, Gallagher, D, Kanneganti, N, McQueney, M, Swanson, R . 2013. A Robust Ultra-High-Throughput Screening Assay for DEK Binding to DNA. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013

Stroke, IL, Sturzenbecker, LJ, Letourneau, JJ, Quintero, JG, Sabalski, Joan E, Marinelli, B, Pechik, I, Diller, D, Paulish-Miller, T, Hilbert, DW., Gygax, S, Stein, P, Webb, M. 2013. High throughput screening of combinatorial libraries for inhibitors of Clostridium difficile toxins. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013

Stein, P. 2013. Simple and Complex Science and Technology. Rutgers University, November 21, 2013

Ranguelova K, Rice A, Lardinois O, Triquigneaux M, Steinckwich N, Deteding L, Stravos G, Mason RP. 2013. Sulfite-mediated oxidation of myeloperoxidase to a free radical: immuno-spin trapping detection in human neutrophils. Free Radic Biol Med (60): 98-106

Khazak V, Eyrisch S, Kato J, Tamanoi F, Golemis EA. 2013. A two-hybrid approach to identify inhibitors of the RAS-RAF interaction. Enzymes. 2013;33 Pt A:213-48. doi: 10.1016/B978-0-12-416749-0.00010-5.

Van Zandt, Michael; Jagdmann, Jr., Gunnar Erik. 2013. Ring constrained analogs as arginase inhibitors, WO 2013158262, 52 pp (2013)

Golebiowski, Adam; Whitehouse, Darren; Beckett, R. Paul; Van Zandt, Michael; Ji, Min Koo; Ryder, Todd R.; Jagdmann, Erik; Andreoli, Monica; Lee, Yung; Sheeler, Ryan; et al. 2013. Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction, Bioorganic & Medicinal Chemistry Letters (2013), 23(17), 4837-4841 PMID: 23886684

Zhang, Mingbao; Jagdmann, G. Erik, Jr.; Van Zandt, Michael; Beckett, Paul; Schroeter, Hagen. 2013. Enantioselective synthesis of orthogonally protected (2R,3R)-(-)-epicatechin derivatives, key intermediates in the de novo chemical synthesis of (-)-epicatechin glucuronides and sulfates, Tetrahedron Asymmetry (2013), 24(7), 362-373

Van Zandt, Michael C.; Whitehouse, Darren L.; Golebiowski, Adam; Ji, Min Koo; Zhang, Mingbao; Beckett, R. Paul; Jagdmann, G. Erik; Ryder, Todd R.; Sheeler, Ryan; Andreoli, Monica; et al. 2013. Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl) hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury, Journal of Medicinal Chemistry (2013), 56(6), 2568-2580 PMID: 23472952

Golebiowski, Adam; Paul Beckett, R.; Van Zandt, Michael; Ji, Min Koo; Whitehouse, Darren; Ryder, Todd R.; Jagdmann, Erik; Andreoli, Monica; Mazur, Adam; Padmanilayam, Manyian; et al. 2013. 2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors, Bioorganic & Medicinal Chemistry Letters (2013), 23(7), 2027-2030 PMID: 23453840

Zhang, Mingbao; Jagdmann, G. Erik; Van Zandt, Michael; Sheeler, Ryan; Beckett, Paul; Schroeter, Hagen. 2013. Chemical Synthesis and Characterization of Epicatechin Glucuronides and Sulfates: Bioanalytical Standards for Epicatechin Metabolite Identification, Journal of Natural Products (2013), 762), 157-169 PMID: 23356946

McQueney, MS, Uveges, A, Malone, J, O’Brien, L, Cole, A, Webb, M. 2012. An Ultra High Throughput Screen of the Venenum Discovery Library for PARP-1 Inhibitors for The 17th International Inflammation Research Association Conference (Lake George, New York) 9-13 September, 2012

Stroke, IL, Hilbert, DW, Letourneau, JJ, Paulish-Miller, T, Quintero, JG, Sabalski, JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012

Beasley, JR, Malone, J, O’Brien, L, Huang, C, Sieber-McMaster, E, Shi, D, Xu, X, Nawoschik, S, Pham, Q, Webb, M. 2012. Discovery of GPBAR1 (TGR5) Agonists from a 1536-well UHTS of the ECLiPS Compound Collection. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012

Stroke IL, Hilbert DW, Letourneau JJ, Paulish-Miller T, Quintero JG, Sabalski JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012

Webb, M. 2012. How to Mine Novel Biology Space with Technology Picks and Shovels. Kean University, March 12, 2012

Webb, M. 2012. The Pivitol Role of Vertical Integration in Biotechnology. Rutgers University, November 5, 2012

Hayward, MD, Dogan RE, Buiakova O, Grass DS, Phelan JM, Wissenbach M. 2012. Physiological and Behavioral Characterization of C57BL/6NTac and Balb/C Mice 63rd AALAS, Minneaposlis, November 4-8, 2012

Scheer N, Balimane P, Hayward M.D., Buechel S, Kauselmann G, Wolf CR. 2012. Generation and Characterization of a Novel MRP2 Humanized Mouse Line Drug Metab Dispos 40(11):2212-8

Sesma JI, Kreda SM, Steinckwich-Besancon N, Dang H, García-Mata R, Harden TK, Lazarowski ER. 2012. The UDP-sugar-sensing P2Y14 receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils. Am J Physiol Cell Physiol 303(5): C490-8

Kobayashi DT, Decker D, Zaworski P, Klott K, McGonigal J, Ghazal N, Sly L, Chung B, Vanderlugt J, Chen KS. 2012. Evaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein. PLoS One. 2012;7(11):e50763 PMID: 23226377

Hayward MD, Buiakova O, Grass D. 2011. Minimizing Strain Influences in a Genetically Modified Mouse Phenotyping Platform Ann N Y Acad Sci 1245: 27-30

Michael D. Hayward, Trisha Chu, Steve Karagrigoriou, Duo Chen, William Campbell, Cristina Mottershead, Arthur Wozniczka, Gerald Bothe, Jennifer Phelan, David S. Grass and Olesia Buiakova. 2011. A Comparison of Metabolic Characteristics Among C57BL/6NTac, C57BL/6J and C57BL/6JBom Diet Induced Obese Mice With Environmental Conditioning. 62nd AALAS, San Diego October 2-6 2011

Huang C, Zhao J, Simhadri S, Webb M, Ohlmeyer M, Zhi L. 2011. Discovery of a Novel Series of mGluR5 Antagonists. Gordon Research Conference, Medicinal Chemistry, Colby- Sawyer College, New London, NH, August 7-12, 2011

Swanson, RN, Stroke, IL, Manners, MT, Gallo-Ebert, C, Nickels, J. 2011. Engineering Transcription Factors for Use in Ultra-High Throughput DNA Binding Assays. 7th Annual Protein Engineering Summit (Boston, Massachusetts) 9-13 May, 2011

Stroke, IL, Manners, MT, Swanson, RN, Dimitrov, D, Gallo-Ebert, C, Nickels, J. 2011. Targeting the Transcription Factor Upc2 for Antifungal Drug Discovery. Society for Biomolecular Sciences Annual Meeting (Orlando, Florida) 16-31 March, 2011

Hayward, Michael D., Trisha Chu, Steve Karagrigoriou, Duo Chen, William Campbell, Cristina Mottershead, Arthur Wozniczka, Gerald Bothe, Jennifer Phelan, David S. Grass and Olesia Buiakova. 2011. A Comparison of Metabolic Characteristics Among C57BL/6NTac, C57BL/6J and C57BL/6JBom Diet Induced Obese Mice With Environmental Conditioning, ENDO 2011 Boston, June 4-7 2011

Kruijf PD, Lim HD, Roumen L, Renjaan VA, Zhao J, Webb ML, Auld DS, Wijkmans JCHM, Zaman GJR, Smit MJ, Graaf CD, Leurs R. 2011. Identification of a Novel Allosteric Binding Site in the CXCR2. Chemokine Recept Mol Pharmacol 80:1108-1118 PMID: 21948388

Steinckwich N, Schenten V, Melchior C, Bréchard S, Tschirhart EJ. 2011. An essential role of STIM1, Orai1, and S100A8-A9 proteins for Ca2+ signaling and Fc?R-mediated phagosomal oxidative activity. J Immunol 186(4): 2182-91

Schenten V, Melchior C, Steinckwich N, Tschirhart EJ, Bréchard S. 2011. Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9. J Leukoc Biol 89(4): 587-96

Forde EA, Dogan RE, Karpus WJ. 2011. CCR4 contributes to the pathogenesis of experimental autoimmune encephalomyelitis by regulating inflammatory macrophage function. J Neuroimmunol 239(1):17-26

Dogan RE, Elhofy A, Karpus WJ. 2011. CCL22 (MDC) regulates Experimental Autoimmune Encephalomyelitis (EAE) by controlling inflammatory macrophages accumulation and effector function. J Leukoc Biol 89(1): 93-104

Chen J, Siew H, Hayward M, Raisinghani M, Buiakova O, Parker R. 2010. Comprehensive Phenotype of Mice with PCSK9-Y119X Null Mutation PCSK9: from Gene to Therapeutics, Nantes France, 11-13 March 2010

Buiakova O, Xu Y, Seibler J, Kissel H, Roschmann E, Michalak E, Nacerddine K, van Lohuizen M, Jonkers J, Grass D. 2010. New tools to evaluate genetic targets and therapeutic strategies against cancer: in vivo imaging and inducible systems to modify gene function, European Journal of Cancer Supplements, Volume 8, issue 5 (June, 2010), p. 95

Hayward MD, Campbell W, Karagrigoriou S, Chen D, C Chu C, Woczniczka A, McBride M, Petralia S, Grass DS Buiakova O. 2010. Mouse Models of Human Cholesterol Metabolism for Pre-Clinical Studies of Lipid Homeostasis ENDO 2010 San Diego, 19-22 June 2010

Xu Y, Roschmann E, Buiakova O, Grass D.. 2010. Bioluminescent imaging in evaluation of therapeutic strategies against cancer: Focus on orthotopic xenograft tumor models with spontaneous metastases, European Journal of Cancer Supplements, Volume 8, issue 7 (November, 2010), p. 91

González-Pérez V, Reiner DJ, Alan JK, Mitchell C, Edwards LJ, Khazak V, Der CJ, Cox AD. 2010. Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells. J Mol Signal;5:2. doi: 10.1186/1750-2187-5-2.

Ho SB, Luu Y, Shekels LL, Batra SK, Kandarian B, Evans DB, Zaworski PG, Wolfe CL, Heinrikson RL. 2010. Activity of recombinant cysteine-rich domain proteins derived from the membrane-bound MUC17/Muc3 family mucins. Biochim Biophys Acta 1800(7):629-38. Epub 2010 Mar 20. PMID: 20332014

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