Genesis Biotechnology Group
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Target Validation

Stage

  • Cell based assay development and miniaturization
  • Protein Purification and Expression
  • In-vitro target validation
  • Biochemistry and biomarker development
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HTS

Stage

  • 5.6M compound ECLiPS library
  • uHTS capabilities
  • Compound and data management
  • Target deconvolution
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Hit

Stage

  • Compound synthesis
  • Medicinal, analytical and computational chemistry
  • Crystallography and structure-based drug design
  • Molecular modelling and protein crystallization
  • Expertise in hit-to-lead and lead optimization in broad therapeutic disease areas such as Immuno-oncology, Oncology, Metabolic, Infectious, and CNS diseases.
  • Chemists have multi-year experience from both big pharma and biotech companies.
  • Five chemistry labs, 22 hoods.
  • In house 400 MHz NMR, 3 analytical LC/MS systems, mass-directed purification system
  • In house ADME, DMPK and in vivo studies.
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